Clinical Trial » Intervention type » Procedure

Procedure

Development of Imaging, Clinical and Biochemical Bio-Markers for Parkinson's Disease
31 May 2009
We propose to build on preliminary data evaluating non-dopaminergic/non-motor clinical biomarkers to more fully assess these markers at the threshold of Parkinson disease (PD). ... 
Controlled Trial of DBS in Early Patients With Parkinsons' Disease
31 May 2009
Parkinsons' disease is one of the most disabling chronic neurological diseases. It can be treated sufficiently until motor complications with fluctuations of mobility and dyskinesias develop. The ... 
The Mood/Cognitive Effects of STN vs. GPi Deep Brain Stimulation in Parkinson's Disease
31 May 2009
The purpose of this trial is to study the mood and cognitive effects of deep brain stimulation in Parkinson's disease. ... 
Effects of Deep Brain Stimulation in Parkinson's Disease
02 Mar 2009
The purpose of this study is to identify factors predicting good results in patients treated with deep brain stimulation for Parkinson's disease. The study includes a comparison of two ... 
Select Stim: Selective Stimulation of the Subthalamic Nucleus in Parkinson's Disease. "A Feasibility Study"
10 Dec 2008
In the advanced stages of Parkinson Disease deep brain stimulation of the subthalamic nucleus (STN DBS) is the next therapeutic option. Despite the beneficial motor effects there are ... 
State Dependent Resonance in the BG-Cortical Loops
25 Feb 2008
Neuronal activity in circuits between the basal ganglia (BG) and motor cortical areas is abnormally synchronized and rhythmic. The oscillatory activity prevails at 8-30 Hz in untreated ... 
Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With Parkinson Disease or Alzheimer Disease and in Healthy Subjects
15 Jan 2008
To assess the dynamic uptake and washout of 123-I CLINDE, a potential imaging biomarker for inflammatory changes in brain, using single photon emission computed tomography (SPECT) in similarly aged ... 
Deep Brain Stimulation in Patients With Parkinson's Disease
20 Dec 2007
The purpose of this study is to determine the effect of deep brain stimulation surgery on movement-related cortical potentials in patients with Parkinson's disease. ... 
Constitution of a Standardized Neural Imaging Database in Healthy Subjects
07 Jun 2007
MRI is a powerful imaging tool used for the precise study of brain morphology (morphometric study, tissue study, study of connectivity). Isotopic examinations by Single Photon Emission Tomography ... 
Efficacy and Safety of F-18 FPCIT PET in Parkinson's Disease and Essential Tremor Patients
29 Apr 2007
The purpose of this study is to determine whether F-18 FPCIT is effective and safe radiopharmaceutical for the objective diagnosis of Parkinson's disease. ... 
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