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Interesting results from North Arab-Berber population comparing LRRK2, PINK1, and genetically undefined PD

14 Oct 2009 03:51 PM EST
Research into the understanding of how LRRK2 is linked to PD has been a priority focus for MJFF for the past few years.  We have committed our effort to addressing several of the pre-clinical ... 
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This recent paper compares clinical phenotypes in PD patients with LRRK2 mutations, PINK1 mutations, or genetically undefined familial PD.  The authors identify some clinical differences between the groups suggesting an associationg between specific genetic causes of PD and clinical phenotypes.  It is of interest to determine whether these same correlations are found in other populations.