Clinical Trials

Treadmill Training With Additional Body Load: Effects on Gait of Subjects With Parkinson´s Disease

Universidade Federal de Sao Carlos
Parkinson's Disease (PD)
Behavioral
exercise
The purpose of this study was to assess the effects of treadmill walking training with additional body load on the ground reaction forces, spatiotemporal, and kinematic variables of the gait of Responses: 0 ... 

Parcopa Versus Carbidopa-Levodopa in a Single Dose Cross-Over Comparison Study

Baylor College of Medicine
Parkinson's Disease (PD)
Drug
parcopa
To find out if a single dose of Parcopa®, a form of levodopa that dissolves in your mouth, works faster than regular oral levodopa which is swallowed, in fluctuating PD patients. Responses: 0 ... 

Transcranial Electrical Polarization to Treat Symptoms of Parkinson's Disease

National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson's Disease (PD)
transcranial direct current stimulation
This study will examine the effects of transcranial electrical polarization (TEP) on gait (walking) problems and rigidity in patients with Parkinson's disease. TEP is a method of brain Responses: 0 ... 

Preparation for compensatory forward stepping in Parkinson's disease

Parkinson's Disease
Observational study to determine the preparation for compensatory stepping in PD patients and see whether levodopa improves this. Responses: 0 ... 

Efficacy and Safety of Levetiracetam Versus Placebo on Levodopa-induced Dyskinesias in Advanced Parkinson's Disease (LeLeDys)

Dresden University of Technology
Parkinson's Disease
Drug
levetiracetam
The study is designed to measure the efficacy and safety of levetiracetam on levodopa-induced dyskinesias in late-stage Parkinson's disease. The patients are planned to be treated with levetiracetam Responses: 0 ... 

Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease (STEADY-PD)

The Parkinson Study Group
Parkinson Disease
Drug
Dynacirc CR (Isradipine)
The Parkinson Study Group is conducting a research study of Dynacirc CR (Isradipine) to find out if it can be used safely, is tolerated by patients with Parkinson Disease (PD) and if it slows the Responses: 2 ... 

Effectiveness of an Active Lifestyle Promotion Program for Patients With Parkinson's Disease (ParkFit)

Radboud University
Parkinson's Disease (PD)
physical activity
Patients with Parkinson's disease (PD) are heavily inclined towards a sedentary lifestyle. This is caused by a combination of physical impairments and cognitive dysfunction. However, regular Responses: 0 ... 

A Placebo- and Active-Controlled Study of Preladenant in Early Parkinson's Disease

Schering-Plough
Early Parkinson's Disease
Drug
preladenant
This is a one year, 2-part study to determine the efficacy and safety of preladenant, an adenosine type 2a (A2a) receptor antagonist. The purpose of Part 1 (first 26 weeks) is to determine if Responses: 1 ... 

A Double-Blind, Randomized, Placebo and Active-Controlled Study of Nebicapone for the Treatment of Motor Fluctuations in Parkinson's Disease

Parkinson's Disease (PD)
Drug
nebicapone
This is a study to determine the efficacy, safety, and tolerability of nebicapone, a COMT inhibitor, to treat PD. Responses: 0 ... 

Controlled Trial on the Effect of 10 Days Low-Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Motor Signs in Parkinson's Disease

Parkinson's Disease (PD)
rTMS
Low-frequency rTMS was investigated for its effect on motor signs in PD. The authors conclude that the protocol has no therapeutic value. Responses: 0 ...