We tested these MJFF LRRK2 antibodies by western blot in the brains from wild type mice and human LRRK2 mutant G2019S (Flag tagged) transgenic mice which were made by our lab. ...
We have tested anti-LRRK2 rabbit monoclonal antibodies for expression of endogenous proteins in different cell lines and mouse brain by western blot. Clones c5-8, 41-2 and 69-6 were the most ...
The MJFF rabbit anti-LRRK2 monclonal antibodies were tested for western blot detection of endogenous LRRK2 in the human neuroblastoma cell line SHSY5Y and in the mouse fibroblast cell line NIH3T3. We ...
Brain treatment and
Immunohistochemistry: FLAG-LRRK2-WT
transgenic mouse and littermate non-transgenic control mouse were anesthetized and perfused with
30ml cold PBS (pH 7.4) and 30ml 4% ...
I have recently tested the antibodies in 3T3 and Sy5 cell lysates, as well as liver and brain homogenates (from both mice and rats). I am having trouble distinguishing which of the two LRRK2 bands I ...
In zebrafish, we find that antibodies MJFF-1,2, and 3 are somewhat similar in detecting a specific protein product, though at a size much smaller than the expected 280kDa. In rat controls, the ...
We found that c41-2 and c68-7 exhibited a finely punctate staining pattern in the neurites of differentiated human SH-SY5Y cells. The other antibodies showed only non-specific diffuse, faint ...
Researchers at University College London Hospitals (U.K.) are starting a clinical trial to test Exenatide, a synthetic version of a compound originally found in Gila monster saliva. MJFF has funded ...
According to an article in The Scientist, NIH Director Francis Collins says that he was "stunned" by the recent ruling halting research on embryonic stem cells. ...
The American Society for Investigative Pathology has given Charleen T. Chu, associate professor at the University of Pittsburgh, their Outstanding Investigator Award. In a recent paper published in ...