Related Clinical Trials

Riluzole to Treat Parkinson's Disease
This study will evaluate the effects of the drug riluzole on Parkinson's disease symptoms and on dyskinesias (involuntary movements) that develop as a result of long-term treatment with levodopa. ... 
Electronic Compliance Monitoring in Parkinson's Disease
Patients with Parkinson's Disease (PD) depend on medication for relief of motor symptoms, and for this reason are often assumed to medicate very carefully. Overall, medication adherence is very good, ... 
12-Week, Double-Blind, Placeob-Controlled Study of 20 and 60 mg/Day Istradefylline in Parkinson's Disease Patients on Levodopa/Carbodopa
A 12-week, multicenter, double-blind, randomized study designed to evaluate the safety and efficacy of 20 and 60 mg/day istradefylline compared with placebo in subjects with OFF-time phenomena and ... 
Cardiac Valve Complications in Prolactinomas Treated With Cabergoline
Dopamine agonists are first-line agents for the treatment of prolactinomas (1) and Parkinson's disease (2). There is evidence supporting a causal relationship between the occurrence of drug-induced ... 
Developing Objective Measures of Levodopa Induced Dyskinesia: (Study 1)
The ultimate goal of this proposal is to reduce dyskinesia in Parkinson's Disease (PD) patients. Dyskinesias are abnormal movements, often caused by the standard treatment forPD symptoms, levodopa. ... 
Low Dose Apomorphine and Parkinsonism
The purpose of this study is to determine if low doses of apomorphine worsen the motor symptoms of Parkinson's disease. ... 
Cognitive Benefits of Treating Sleep Apnea in Parkinson's Disease
Patients with sleep disordered breathing (SDB), also called sleep apnea, experience nighttime disrupted sleep and, because they stop breathing for short periods during the night, do not get ... 
Treatment of Parkinson's Disease With a Transdermal Skin Patch
Patients with Parkinson's disease are missing the chemical neurotransmitter dopamine. This occurs as a result of destructive changes in an area of the brain responsible for making dopamine, the basal ... 
Overnight Switch Trial From Pramipexole IR to Pramipexole ER in Patients With Early Parkinson Disease
The objectives of this trial conducted in early Parkinson¿s disease (PD) patients are: - To assess if patients with early Parkinson¿s disease (PD) can be successfully switched ... 
Efficacy and Safety of Levetiracetam Versus Placebo on Levodopa-Induced Dyskinesias in Advanced Parkinson's Disease
The study is designed to measure the efficacy and safety of levetiracetam on levodopa-induced dyskinesias in late-stage Parkinson's disease. The patients are planned to be treated with levetiracetam ...