I think the answer is yes, and here is evidence. Part of this work was presented at the XVIII WFN World
Congress on Parkinson's Disease and Related Disorders.
ABSTRACT ...
The delineation of PD into subtypes may have some commercial and/or grant funding advantages since the subtypes may be classified as "orphan diseases" which place them in a different funding ...
In practicality most people are in between tremor dominant and PIGD, so maybe the better question is whether there are PD subtypes relevant for PD therapeutic development. ...
Alberto Espay posted about how PD diagnostic categories can gloss over the phenotypic complexity of movement and therefore hide the possible presence of disease subtypes. Is this also true ...
Among the benefits of enhancing our knowledge on PD subtyping are the better focusing of target populations for clinical trials. At stake is who may and may not ...
The MJFF has identified improving the understanding of PD subtypes as a priority research area for 2010. Improving our understanding of PD subtypes can directly optimize the use of current PD ...
With gene identification we have an opportunity to perform “genotype-phenotype” correlations and determine if specific mutations are associated with particular subtypes. For the most ...
This recent paper compares clinical phenotypes in PD patients with LRRK2 mutations, PINK1 mutations, or genetically undefined familial PD. The authors identify some clinical differences between ...
