The Michael J. Fox Foundation for Parkinson’s Research today announced $3.5 million in total funding to nine research studies aiming to advance understanding of the LRRK2 gene, a promising ...
Hot off the Neuron
presses!! Is alpha-synuclein aggregation and subsequent neurodegeneration
exacerbated by LRRK2? In a tour de force, Huaibin Cai’s group generated
multiple LRRK2 ...
A new study published in the Journal of Neuroscience characterizes the phenotype of a LRRK2 knockout mouse. These mice are viable and show no major abnormalities, including a normal dopaminergic ...
The Michael J. Fox Foundation for Parkinson’s Research today announced $5.2 million in support for two studies defining the clinical presentation of Parkinson’s disease in two specific ...
MJFF is hosting a Summit on LRRK2 in New York tomorrow (Wednesday). Drs. Sonal Das and Brian Fiske want to hear from those of you not attending the meeting - how should MJFF prioritize LRRK2 funding ...
A new study published this week in Nature Cell Biology demonstrates a novel function for parkin: transcriptional repression of the tumor suppressor p53. Parkin is strongly associated with autosomal ...
A new report in Nature Neuroscience by Dr. Alexander Whitworth and colleagues identify a protective pathway (4E-BP-regulated protein translation) that can be stimulated to prevent pathology
in both ...
A major lead for potential new treatments for
Parkinson’s has been discovered by UK researchers in a study primarily
funded by the Parkinson’s Disease Society. ...
A discussion of the new BAC Lrrk2 mouse model developed by Dr. Chenjian Li and colleagues, published today in Nature Neuroscience. Dr. Kirsten Carlson of The Michael J. Fox Foundation, which ...