We tested these MJFF LRRK2 antibodies by western blot in the brains from wild type mice and human LRRK2 mutant G2019S (Flag tagged) transgenic mice which were made by our lab. ...
We have tested anti-LRRK2 rabbit monoclonal antibodies for expression of endogenous proteins in different cell lines and mouse brain by western blot. Clones c5-8, 41-2 and 69-6 were the most ...
The MJFF rabbit anti-LRRK2 monclonal antibodies were tested for western blot detection of endogenous LRRK2 in the human neuroblastoma cell line SHSY5Y and in the mouse fibroblast cell line NIH3T3. We ...
Brain treatment and
Immunohistochemistry: FLAG-LRRK2-WT
transgenic mouse and littermate non-transgenic control mouse were anesthetized and perfused with
30ml cold PBS (pH 7.4) and 30ml 4% ...
I have recently tested the antibodies in 3T3 and Sy5 cell lysates, as well as liver and brain homogenates (from both mice and rats). I am having trouble distinguishing which of the two LRRK2 bands I ...
In zebrafish, we find that antibodies MJFF-1,2, and 3 are somewhat similar in detecting a specific protein product, though at a size much smaller than the expected 280kDa. In rat controls, the ...
We've sent out LRRK2 antibodies to over 160 labs, and more than half have submitted their data to MJFF so far. Our summary, posted on the LRRK2 antibody discussion page, points out the strengths and ...
The
Alzheimer’s Drug Discovery Foundation (ADDF) and The Association for Frontotemporal
Dementias (AFTD) have announced funding opportunities for research on frontotemporal dementias. The ...
The European Patent Office (EPO) has given Amarantus Therapeutics a Notice of Allowance on mesencephalic astrocyte-derived neurotrophic factor (MANF), which is in preclinical development. According ...
The National Institute of Neurological Disorders and Stroke (NINDS) wants to know what researchers think about tool and resource development needs in the neuroscience and neurology fields. ...