VPS41, a protein thought to be involved in the docking and fusion of lysosomal vesicles, was recently identified as a neuroprotective gene in a C. elegans
study (Hamamichi et al., 2008). Studies ...
RTP801 (Redd1, Dig2, DDIT4, FLJ20500, RP11-442H21.1) inhibits mTOR activity and is known to be upregulated in response to cellular stresses including DNA damage, oxidative stress,
hypoxia and ...
VMAT2 inhibitors are currently used to treat other related disorders,
including chorea in HD patients. VMAT2 (along with other markers of dopamine transport) is currently under investigation
as a ...
