Holli Kawadler, PhD

Job title:

Research Officer, PD Online Research

Organization:

The Michael J. Fox Foundation for Parkinson's Research (MJFF)

Bio:

Holli Kawadler joined the Michael J. Fox Foundation in February 2009 to make PD Online Research a success! She received her undergraduate degree in Biology with a concentration in neurobiology and behavior from Cornell University and her PhD in Pharmacology from the University of Pennsylvania School of Medicine. Dr. Kawadler completed her graduate work studying cell death pathways in the laboratory of Dr. Xiaolu Yang. Her dissertation explored the paradoxical roles of death proteins in growth signaling during immune responses, focusing on the regulation and function of caspases in T lymphocyte proliferation.

Technology:

molecular biology

PD Guide Terms:

PARK1/4 (SNCA/Alpha-Synuclein)

Stem Cells

Targeting Pathogenic Mechanisms

Neuroimmune Signaling Pathways

PARK2 (Parkin)

Pathogenic Mechanisms

Protein Degradation Pathways

Neuroimmune Function

PARK8 (LRRK2)

Programmed Cell Death

Investigative Tools

The Business of Science

Contributions:

Published Contributions:

New review on placebo response

response to: What are the biological and psychosocial mechanisms of the placebo response, and how can we manage and/or tap the placebo response in PD clinical trials?

19 Feb 2010 12:34 PM EST

The recent review by Drs. Finniss, Kaptchuk, Miller and Benedetti of the placebo effect in clinical research explores the mechanistic, clinical and ethical questions that surround this complex ...

ESC v. iPSC: The difference is in efficiency

response to: Can induced pluripotent stem cells be used to generate useful Parkinson's disease cell models?

18 Feb 2010 12:20 PM EST

There are still a number of questions to consider when looking at using iPS in both regenerative medicine and disease modeling, as outlined previously. How similar are ES and iPS cells, can we ...

Linking LRRK2 and alpha-synuclein

response to: LRRK2 and alpha-synuclein: Made for each other?

12 Feb 2010 05:07 PM EST

A recent paper, published in Cell Signaling, also provides support for a link between LRRK2 and alpha-synuclein through a common pathway. As stated eloquently by Dr. Moore, there a number of possible ...

Workgroups: