Zhenyu Yue, Ph. D.

Job title:

Associate Professor

Organization:

Mount Sinai School of Medicine

Technology:

biochemistry

cell biology; molecular biology; animal models

PD Guide Terms:

Etiology

Therapeutic Development

Contributions:

Published Contributions:

Characterization of new BAC LRRK2 WT and G2019S mouse models - Q&A with Dr. Zhenyu Yue

response to: New PD models available through MJFF-Jackson Labs partnership

4 Feb 2010 11:25 AM EST

Dr. Zhenyu Yue of Mount Sinai School of Medicine discusses two new BAC Lrrk2 mouse models, recently published in Journal of Neuroscience. As The Michael J. Fox Foundation partially funded this ...

Is LRRK2 kinase activity the real culprit?

response to: What do we know about the function of LRRK2 in cellular processes that may shed light on its role in PD pathogenesis? Is LRRK2 kinase activity key to this regulation or do other features/functions of LRRK2 contribute?

29 Jul 2009 06:44 PM EST

Although LRRK2 is considered one of the most promising drug targets for PD, currently we know very little about its biological function and structure, or how LRRK2 mutations affect its functions that ...