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Yee RE, Irwin I, Milonas C, Stout DB, Huang SC, Shoghi-Jadid K, et al. Novel observations with FDOPA-PET imaging after early nigrostriatal damage. Mov Disord. 2001;16(5):838-48.
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Yee RE, Huang SC, Stout DB, Irwin I, Shoghi-Jadid K, Togaski DM, et al. Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations. J Neurochem. 2000;74(3):1147-57.
McGrew DM, Irwin I, Langston JW. Ethylenebisdithiocarbamate enhances MPTP-induced striatal dopamine depletion in mice. Neurotoxicology. 2000;21(3):309-12.
Walters TL, Irwin I, Delfani K, Langston JW, Janson AM. Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP. Exp Neurol. 1999;156(1):62-70.
Irwin I, Delanney L, Chan P, Sandy MS, Di Monte DA, Langston JW. Nigrostriatal monoamine oxidase A and B in aging squirrel monkeys and C57BL/6 mice. Neurobiol Aging. 1997;18(2):235-41.
Di Monte DA, Delanney LE, Irwin I, Royland JE, Chan P, Jakowec MW, et al. Monoamine oxidase-dependent metabolism of dopamine in the striatum and substantia nigra of L-DOPA-treated monkeys. Brain Res. 1996;738(1):53-9.
Beck KD, Irwin I, Valverde J, Brennan TJ, Langston JW, Hefti F. GDNF induces a dystonia-like state in neonatal rats and stimulates dopamine and serotonin synthesis. Neuron. 1996;16(3):665-73.
Di Monte DA, Royland JE, Irwin I, Langston JW. Astrocytes as the site for bioactivation of neurotoxins. Neurotoxicology. 1996;17(3-4):697-703.
Forno LS, Delanney LE, Irwin I, Langston JW. Electron microscopy of Lewy bodies in the amygdala-parahippocampal region. Comparison with inclusion bodies in the MPTP-treated squirrel monkey. Advances in neurology. 1996;69:217-28.
Tetrud JW, Langston JW, Irwin I, Snow B. Parkinsonism caused by petroleum waste ingestion. Neurology. 1994;44(6):1051-4.
Chan P, Di Monte DA, Luo JJ, Delanney LE, Irwin I, Langston JW. Rapid ATP loss caused by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. J Neurochem. 1994;62(6):2484-7.
Irwin I, Delanney LE, McNeill T, Chan P, Forno LS, Murphy GM, et al. Aging and the nigrostriatal dopamine system: a non-human primate study. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. 1994;3(4):251-65.
Forno LS, Delanney LE, Irwin I, Langston JW. Evolution of nerve fiber degeneration in the striatum in the MPTP-treated squirrel monkey. Mol Neurobiol. 1994;9(1-3):163-70.
Kurth MC, Tetrud JW, Tanner CM, Irwin I, Stebbins GT, Goetz CG, et al. Double-blind, placebo-controlled, crossover study of duodenal infusion of levodopa/carbidopa in Parkinson's disease patients with 'on-off' fluctuations. Neurology. 1993;43(9):1698-703.
Kurth MC, Tetrud JW, Irwin I, Lyness WH, Langston JW. Oral levodopa/carbidopa solution versus tablets in Parkinson's patients with severe fluctuations: a pilot study. Neurology. 1993;43(5):1036-9.
Chan P, Langston JW, Irwin I, Delanney LE, Di Monte DA. 2-deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain. J Neurochem. 1993;61(2):610-6.
Graybiel AM, Moratalla R, Quinn B, Delanney LE, Irwin I, Langston JW. Early-stage loss of dopamine uptake-site binding in MPTP-treated monkeys. Advances in neurology. 1993;60:34-9.
Irwin I, Delanney LE, Langston JW. MPTP and aging. Studies in the C57BL/6 mouse. Advances in neurology. 1993;60:197-206.
Forno LS, Delanney LE, Irwin I, Langston JW. Similarities and differences between MPTP-induced parkinsonsim and Parkinson's disease. Neuropathologic considerations. Advances in neurology. 1993;60:600-8.
Moratalla R, Quinn B, Delanney LE, Irwin I, Langston JW, Graybiel AM. Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA. 1992;89(9):3859-63.
Irwin I, Finnegan KT, Delanney LE, Di Monte D, Langston JW. The relationships between aging, monoamine oxidase, striatal dopamine and the effects of MPTP in C57BL/6 mice: a critical reassessment. Brain Res. 1992;572(1-2):224-31.
Forno LS, Delanney LE, Irwin I, Di Monte D, Langston JW. Astrocytes and Parkinson's disease. Prog Brain Res. 1992;94:429-36.
Koller WC, Langston JW, Hubble JP, Irwin I, Zack M, Golbe L, et al. Does a long preclinical period occur in Parkinson's disease? Neurology. 1991;41(5 Suppl 2):8-13.
Chan P, Delanney LE, Irwin I, Langston JW, Di Monte D. Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. J Neurochem. 1991;57(1):348-51.
Koller WC, Langston JW, Hubble JP, Irwin I, Zack M, Golbe L, et al. Does a long preclinical period occur in Parkinson's disease? Geriatrics. 1991;46 Suppl 1:8-15.