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Discussion: MJFF Closed Next Week
New Discussion by Katie Cottingham 27 Aug 2010

MJFF will be closed next week, but we'll be back on September 7, 2010!...

News post: Members in the News: Charleen T. Chu Receives Outstanding Investigator Award
Responses: 1
Latest post by Katie Cottingham 26 Aug 2010

Here's the reference:...

News post: Cognitive Problems May Precede PD Motor Symptoms
Responses: 1
Latest post by Katie Cottingham 25 Aug 2010

Here's the paper:...

PD Guide: Systems Approaches to Parkinson's Disease
Responses: 15
Latest post by Hugo Geerts 25 Aug 2010

I am convinced that computer-based mathematical simulation of physiological and pathological processes does have its place in the research for a treatment of Parkinson’s disease. As a starter, m...

News post: Federal Funding of Embryonic Stem Cells Halted
Responses: 1
Latest post by Katie Cottingham 25 Aug 2010

The federal government plans to appeal the decision. In the meantime, researchers who already received their checks from NIH this year can spend those funds. However, those still awaiting checks (many...

Clinical trial: A Placebo- and Active-Controlled Study of Preladenant in Early Parkinson's Disease
Responses: 1
Latest post by Michael A Schwarzschild, MGH 25 Aug 2010

Interestingly in addition to assessing for anti-parkinsonian symptomatic benefits through its primary outcome measure and for safety and tolerability, this large phase III RCT of an adenosine A2A re...

Paper: Calcium channel blocker use and risk of Parkinson's disease.
Responses: 3
Latest post by Mauro Fasano 24 Aug 2010

I appreciated this report. Indeed, we found that calcium channels are downregulated in SNpc of PD patients. See Basso et al., 2004 ...

Discussion: Papers of the Week: August 23, 2010
New Discussion by Katie Cottingham 23 Aug 2010

Below are the Papers of the Week. To comment on an individual paper, click on the manuscript title, then click "reply"....

Paper: Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study.
Responses: 5
Latest post by Katie Cottingham 23 Aug 2010

FDA is studying Stalevo (carbidopa/levodopa plus entacapone) to see whether the drug increases the risk of cardiovascular problems. The data seem to suggest that an increased risk is possible, but mor...

News post: Night of the Living Dead...Gene?!
Responses: 1
Latest post by Brian K. Fiske, The Michael J. Fox Foundation for Parkinson's Research 19 Aug 2010

Anyone looking at this sort of idea as possible cause for parkinsonism? Would this be seen in existing genetic datasets or would we need to do more specialized sequencing to look for it in people with...